Not really ! The whole OM is rather built around the principle of dragging things about with a mouse, which although in most cases is its best feature is also its biggest curse for these vast unorganised scenes we tend to get.
All good tips so far. We should also mention the ability to open more than 1 OM at once so that one can always be scrolled to the top, making dragging things from the other involve less upward scrolling, and also the use of modifier keys when expanding or opening multi-level folders / nulls to speed up readability.
My approach to these things is much like EAlexander's above, I try and use rectangle select in the vp to grab groups of things that seem to belong together, Alt-G them, name and hide the group, then rinse and repeat until there is nothing left in the vp.
CBR