I am hesitant to jump into this one not having a 3D printer myself, and I wouldn't presume that I know anything you don't about this, but I was given to understand that as long as the mesh is watertight it doesn't matter what the topology is doing, short of actual error-state polygons that can't be interpreted as a viable surface properly by the slicer software.
In the absence of any pics or the file, f I had to predict what might be going wrong I would suspect the booleans first, especially if they are layered. But again, I am sure you know every trick I do to try and stop booles failing, and I imagine you can't get sharp enough results out of the volume builder, so it is difficult to know what else to suggest here. Bizarrely the thing that first occurs to me is to remesh it in Zbrush where the extended functionality of Z-remesher might be able to hold on to your hard edges in a way it currently can't in Cinema ?
CBR